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Life Extension


Suitable for Vegetarians

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Life Extension Cytokine Suppress™, 30 vegetarian capsules, is a supplement/vitamin for you if you are interested in inflammation management. Inflammation is a natural process that affects every cell and organ in the body. As we age, maintaining a balanced inflammatory response becomes increasingly important to our health. Fortunately, there is something we can do every day to support this process at a deep molecular level. 

Cytokine Suppress with EGCG provides two natural food ingredients that have the ability to promote a healthy inflammatory immune response. Key constituents found in mung beans and green tea support inflammation. (1-4) This potent benefit is delivered by molecules found primarily in the seed coat of the mung bean and EGCG (epigallocate-chin-3-gallate), the major beneficial component in green tea.(4-6)

Acting together, these mung bean and green tea compounds help regulate healthy levels of a protein molecule known as HMGB1. This molecule is responsible for controlling the signalling compounds known as cytokines that cause inflammation. Mung bean seed coat extract has also been shown to support the body’s natural antioxidant defence system. (4-6) Life Extension® Cytokine Suppress with EGCG supports healthy inflammatory levels, that are so important as we age. (8-10)

Our in-house pharmacist, Shabir Daya has written an article about Cytokine Suppress with EGCG benefits:

Directions: As a food supplement, adults, take one (1) capsule without food, or as directed by a medical practitioner. Do not exceed the daily dose. 

Keep out of reach of children. Do not exceed recommended dose. If you are undergoing treatment for a medical condition or if you are pregnant or lactating, please consult with your medical practitioner first.

A food supplement should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Store tightly closed in a cool and dry place. 

Each capsule provideCytokine Suppress™ mung bean extract (coat) [providing 24 mg vitexin, 24 mg isovitexin] - 240 mg and Epigallocatechin gallate (EGCG) [from green tea extract (leaf)] - 300 mg.

Other ingredients: vegetable cellulose (capsule), dicalcium phosphate, microcrystalline cellulose, silica, stearic acid.

How long does it take for Cytokine Suppress to have a noticeable effect?
Due to our unique biochemistries and lifestyles, the times it takes to notice benefits can vary from person to person. We encourage that the product be taken for at least 3 months on a regular basis before assessing its full effects.

What is the caffeine MG of this dose?
This formula uses 315.8 mg of green tea extract to provide 300mg of Epigallocatechin gallate (EGCG). Each serving contains a caffeine content of NMT (not more than) 0.1%, equivalent to 0.3158 mg.

How important is it to take this apart from food?
Life Extension formulates its product dosing and instructions based on scientific literature. This product is suggested to be taken without food, because there is the concern that EGCG and other components found in mung bean coat extract may interfere with other polyphenols/catechins in food. In one study, it was found that the simultaneous ingestion of dietary proteins reduced the bioavailability of galloylated catechins from green tea in humans.

Does this product contain soy?
This product does not contain any soy.

Is this supplement dairy-free?
This product does not contain any dairy.

Is this gluten free/celiac friendly?
This product does not contain any gluten.

Can you take this while breastfeeding?
We cannot make suggestions for women who are breast feeding as our clinical research is not performed in that aspect, therefore we cannot verify efficacy. We suggest discussing this decision with a physician to determine use.

  1. Crit Rev Food Sci Nutr. 2015;55(7):939-54.
  2. Frontiers in immunology. 2019;10:145-145.
  3. Front Immunol. 2018;9:3160.
  4. Evid Based Complement Alternat Med. 2012;2012:498467.
  5. Biochemical pharmacology. 2011;81(9):1152-1163.
  6. PLoS One. 2007;2(11):e1153.
  7. Mol Med. 2015;21 Suppl 1:S6-s12.
  8. PloS one. 2011;6(6):e21071-e21071.
  9. Food Chem. 2012;135(4):2942-6.
  10. J Proteomics. 2017;161:26-37.

Food supplements should not be used as a substitute for a varied diet. Store in a cool, dry place away from direct sunlight. Keep out of reach of young children. Do not exceed the daily dose.  If pregnant, or breastfeeding, or if you are taking medication, or on medical care, consult your physician prior to use.  While we work to ensure that product information on our website is correct, on occasion manufacturers may alter their ingredient lists.  Actual product packaging and materials may contain more and/or different information than that shown on our website.  All information about the products on our website is provided for information purposes only. We recommend that you do not solely rely on the information presented on our website.  Please always read the labels, warnings, and directions provided with the product before using or consuming a product.  In the event of any safety concerns or for any other information about a product please carefully read any instructions provided on the label or packaging and contact the manufacturer.  Content on this site is not intended to substitute for advice given by medical practitioner, pharmacist, or other licensed health-care professional. Contact your health-care provider immediately if you suspect that you have a medical problem.  Information and statements about products are not intended to be used to diagnose, treat, cure, or prevent any disease or health condition.  The customer reviews are only moderated for offensive content – they should not be regarded as medical or health advice; no reliance should therefore be placed on them; and they are not endorsed by Victoria Health. If you have any health problems or questions regarding the suitability of any product please contact a health professional. Products are not medicinal unless otherwise stated. Victoria Health accepts no liability for inaccuracies or misstatements about products by manufacturers or other third parties. This does not affect your statutory rights.

Product Code: LFX0002